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Unigyl (Metronidazole)

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Unigyl is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Aldezol, Amebidal, Anabact, Anaerobex, Anamet, Bemetrazole, Birodogyl, Buccoval, Dazotron, Dequazol, Dirozyl, Emedal, Etronil, Farnat, Flanizol, Geloderm, Giardyl, Gnostol, Imizine, Kilpro, Litagyl, Mecozol, Medazol, Metrajil, Metrazol, Metrocreme, Metrodal, Metrol, Metrolotion, Metronex, Metronidazole, Metrozin, Metrozole, Minegyl, Molazol, Mtronidazole, Nidazyl, Orvagil, Repligen, Rosasol, Taremis, Tismazol, Trichodazol, Trichozole, Triconex, Tricozyl, Trogyl, Vagimid, Zyomet

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Also known as: Metronidazole


Metronidazole vaginal is used to treat women with vaginal infections (eg, bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing the bacteria or preventing their growth. However, this medicine will not work for vaginal fungus or yeast infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Unigyl. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.


If you overdose Generic Unigyl and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Unigyl overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.


Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Unigyl are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of metronidazole injection in the pediatric population. Safety and efficacy have not been established.

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Geometric error in tissue gamma-counting: methods for minimization. Dual blockade of the renin-angiotensin system in diabetic nephropathy. Mean dmft increased from 1.3 for 0-2-yr-olds to 7.4 for 3-5-yr-olds. Population-based study of exercise habits in the counties of Alt Camp and Conca de Barvera (Tarragona). The technique can be directly used to detect presence or absence of P. Cytokines released by the activated cells modulate the inflammatory events. BMI and WC were negative predictors for all-cause mortality in older Chinese adults living in long-term care facilities. Outpatients aged 18-60, regularly visiting respiratory physicians for SAR, were recruited before the grass (grass cohort) or ragweed pollination period (ragweed cohort).

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A chemically designed enzymatic cleavage site for phosphoproteome analysis. Limited usage of T-cell receptor beta chains and sequences of the complementarity determining region 3 of lymphocytes infiltrating in the liver of autoimmune hepatitis. The feeder density increased gastrointestinal parasite traits (richness, infection probability and intensity of infection), probably due to the contamination of feeding sites with infective parasite forms. HAmCq and MAmCq strains were collected in 2002 from Huntsville and Mobile, AL. The material includes 12 deceased with renal insufficiency, 23 deceased with diabetes mellitus and 26 control cases with lethal cardiovascular diseases (without a history of hepatic, renal or metabolic disturbances). This study gives an extensive overview of the impacts of climate change on the contamination of pre-harvested LGVs and shows that climate change should not be ignored in food safety management and research. Qualitative thematic interviews of seven older patients, five family members and fifteen nurses were conducted.

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PG synthase 1 (PGS-1) message and protein are expressed constitutively in MMC-34 cells and are not modulated by exposure to calcium ionophore or aggregation of IgE receptors. Decellularized porcine heart valves treated with deoxycholic acid (DOA) have demonstrated complete recellularization and absence of calcification when implanted into the pulmonary position in sheep. As a result, information is lacking as to what is the optimal setup for an FSS staircase. Study of kidney function by use of mercury-203 labelled neohydrin. The number of missed colon cancers may be reduced by reading twice or reviewing at a later time all barium enema examinations. Because mammalian cells defective in p53 protein show increased genomic instability, it is tempting to speculate that the instability is due to increased chromosome damage resulting from the lack of a G1 delay. Heterogeneous impacts of gender-interpreted contributing factors on driver injury severities in single-vehicle rollover crashes. Our study identifies novel and substantial alterations of endogenous tau protein in glaucoma, including abnormal subcellular distribution, an altered phosphorylation profile, and neurotoxicity. 20 patients with acute ST-elevation myocardial infarction were treated with primary percutaneous coronary intervention within six hours of onset of symptoms. The current study examined the contribution of marital satisfaction to symptoms of depression among patients with acute coronary syndrome (ACS) and their partners.

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As the process of tumor invasion is mediated in part by the elaboration of proteases and protease inhibitors by tumor cells, we sought to determine the expression of the type-IV collagenases and their inhibitors (tissue inhibitors of metalloproteases, TIMPs) in an MRT from the pineal region of a 9-month-old male. Analysis and crystallization of a 25 kDa C-terminal fragment of cloned elongation factor Ts from Escherichia coli. Pulmonary changes developing after administration of the same dose of anti-glomerular antibodies into the left heart ventricle are of lesser extent and the animals survive. Analysis of heme biosynthesis in catalase and cytochrome deficient yeast mutants. Her twin does not manifest any symptoms or signs of Gaucher disease but suffers from type 1 diabetes mellitus. In diseases showing hypererythropoiesis such as iron deficiency anemia, hemolytic anemia, or in cells obtained from very small premature infants, an increase in glycogen particles was observed in most cases. This study investigated the use of Google Street View (GSV) as a novel research method for collecting alcohol-related data in the urban environment.

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Paraganglionic phaeochromocytoma presenting twelve years after adrenalectomy. Electron micrographs of the transducing phage I3 for Mycobacterium smegmatis strain SN2 revealed a phage with a contractile tail and a head with isometric symmetry and visible capsomeres. The relationship of blast cell glucocorticoid receptor levels to response to single-agent steroid trial and remission response in children with acute lymphoblastic leukemia. The 2nd polymerase chain reaction was used, two geno-type specific primers one was for Japanese S diamox drug uses type the other was for Japanese M type7). Reliability of EuroSCORE II to Predict Long-Term Mortality After Isolated Aortic Valve Operations. References used in the text were assessed according to their level of evidence, and guideline recommendations were graded based on the Oxford Centre for Evidence-Based Medicine Levels of Evidence.

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Analysis of disorders of the structure of the what sinus medicine can you take with zyrtec musculoskeletal stomatognathic system in adolescents based on epidemiological studies. Each subject received overnight polysomnography and two lateral cephalograms at the end-expiration phase (L1) and the Muller maneuver (L2), respectively, to evaluate the facial skeleton and the upper airway and its surrounding structures (soft palate, tongue, epiglottis, and hyoid bone). In this context, a perspective is presented in the end, proposing de novo design of inhibitors which directly interact with the DNA Binding region of the free NF-kappaB (p50 subunit), so as to generate more specific and selective leads of NF-kappaB-DNA binding. Determination of ionized calcium in serum by use of an lon-selective electrode. Single hyperthermia of the animals up to 42 degrees C and thermal shock stages were shown to be followed by suppressed activities of natural killer cells.

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An unusual late complication of ileal conduit diversion is described. Following total abdominal hysterectomy and bilateral salpingo-oophorectomy, the plasma testosterone level fell abruptly. In addition, factors involving general health care and management of blood donors should be employed to further ensure blood safety. The aryl propionic acid derivative dexibuprofen was the most potent antiplatelet drug, and its pharmacodynamic profile is similar to aspirin. In this study, we aimed to explore the risk factors for developing hypernatremia in patients with sepsis, and the prognosis of patients with sepsis with or without hypernatremia was also assessed. We produced oxidized mesangial matrix how long before lamisil tablets work protein using a mixed function oxidase system. Previous studies have demonstrated that pre-pubertal aryl hydrocarbon receptor knockout (AHRKO) mice have slow antral follicle growth and reduced capacity to produce estradiol compared to wild-type (WT) mice. On the same day, an H5N1 HPNAI virus was detected from a pooled tissue sample collected from a dead Common Buzzard found on the Black Sea coast in Bulgaria.

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Once a mutation was detected in the proband, all other participating family members and 100 unrelated control normal individuals were screened for the mutation. Length of hospital stay and number of prescribed drugs are risk factors. The following patterns should be recommended as a criterion of normal vitamin B2 requirements: the FAD-effect is no more than 1.25, the levels of riboflavin, more than 5 ng/ml in the plasma and more than 130 ng/ml in the erythrocytes. We describe an infant in whom closed reduction and pinning were required in order to assure a good outcome. Our data suggest that both the MEK/ERK and PI3K/AKT pathways mediate the stimulatory effect of IGF-I on myoblast proliferation and that the PI3K/AKT pathway mediates this effect through cyclin D2. The histochemical localization of acrosin in guinea-pig sperm after the acrosome reaction. Substantial evidence collected from clinical data and experimental studies has indicated that CNS is not spared from diabetes complications. From dextransucrase analysis, various putative cleavage sites with the same sequence were found in the variable region and in the glucan binding domain. Prevalence and factors influencing pelvic joint and low-back pain during pregnancy are hereby reported.

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